About 4 results found for searched term "B-Raf IN 16" (0.451 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42154 | B-Raf IN 16 | Raf |
| B-Raf IN 16 is a BRAF inhibitors that belongs a cyclic iminopyrimidine derivative. | ||
| M1774 | PLX-4720 | Raf |
| PLX4720 | ||
| PLX-4720 is a selective BRAFV600E inhibitor with the IC50 values of 160 nM and 130 nM for B-Raf and BRK respectively. | ||
| M1783 | SB590885 | Raf |
| SB590885 is a selective small-molecule inhibitor of the B-Raf kinase and Ki values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively. | ||
| M27869 | CCT241161 | Raf |
| CCT241161 is an orally active pan-RAF inhibitor with IC50s of 3, 6, 10, 15 and 30 nM for LCK, CRAF, SRC, V600E-BRAF and BRAF, respectively. CCT241161 shows good activity to in BRAF and NRAS mutant melanomas. CCT241161 also exhibits anticancer cell proliferative activity. | ||
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